Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromatin remodeling regulator CECR2 [424-538]' and Ligand = 'BDBM310907'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chromatin remodeling regulator CECR2 [424-538] (Homo sapiens (Human))	BDBM310907 (3-(6-ethyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,...) Show SMILES CCn1cc(-c2cccc(c2)C(=O)N(C)C)c2cc[nH]c2c1=O Show InChI InChI=1S/C18H19N3O2/c1-4-21-11-15(14-8-9-19-16(14)18(21)23)12-6-5-7-13(10-12)17(22)20(2)3/h5-11,19H,4H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc.; Constellation Pharmaceuticals Inc. US Patent					Assay Description His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...				US Patent US10150767 (2018) BindingDB Entry DOI: 10.7270/Q2V98B5W
					More data for this Ligand-Target Pair