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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Chymotrypsin-like protease CTRL-1' and Ligand = 'BDBM441783'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chymotrypsin-like protease CTRL-1


(Homo sapiens (Human))
BDBM441783
PNG
(US10640533, Identification number CX13-501 | US106...)
Show SMILES COC[C@H](NC(=O)c1cc(C)on1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r|
Show InChI InChI=1S/C26H35N5O7/c1-15(2)10-18(22(32)26(4)14-37-26)28-23(33)19(12-17-6-8-27-9-7-17)29-25(35)21(13-36-5)30-24(34)20-11-16(3)38-31-20/h6-9,11,15,18-19,21H,10,12-14H2,1-5H3,(H,28,33)(H,29,35)(H,30,34)/t18-,19-,21-,26+/m0/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 113n/an/an/an/an/an/a



CENTRAX INTERNATIONAL, INC.

US Patent


Assay Description
Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...


US Patent US10640533 (2020)


BindingDB Entry DOI: 10.7270/Q28G8PQN
More data for this
Ligand-Target Pair
Chymotrypsin-like protease CTRL-1


(Homo sapiens (Human))
BDBM441783
PNG
(US10640533, Identification number CX13-501 | US106...)
Show SMILES COC[C@H](NC(=O)c1cc(C)on1)C(=O)N[C@@H](Cc1ccncc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r|
Show InChI InChI=1S/C26H35N5O7/c1-15(2)10-18(22(32)26(4)14-37-26)28-23(33)19(12-17-6-8-27-9-7-17)29-25(35)21(13-36-5)30-24(34)20-11-16(3)38-31-20/h6-9,11,15,18-19,21H,10,12-14H2,1-5H3,(H,28,33)(H,29,35)(H,30,34)/t18-,19-,21-,26+/m0/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 392n/an/an/an/an/an/a



CENTRAX INTERNATIONAL, INC.

US Patent


Assay Description
Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...


US Patent US10640533 (2020)


BindingDB Entry DOI: 10.7270/Q28G8PQN
More data for this
Ligand-Target Pair