Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2' and Ligand = 'BDBM387057'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2 (Homo sapiens (Human))	BDBM387057 (N′-Cyano-1-(4-methoxyphenyl)-7-oxo-6-(2̸...) Show SMILES COc1ccc(cc1)-n1nc(\C(N)=N/C#N)c2CCN(C3CCN(CC3)N3CCCCC3=O)C(=O)c12 Show InChI InChI=1S/C25H30N8O3/c1-36-19-7-5-18(6-8-19)33-23-20(22(29-33)24(27)28-16-26)11-15-31(25(23)35)17-9-13-30(14-10-17)32-12-3-2-4-21(32)34/h5-8,17H,2-4,9-15H2,1H3,(H2,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2F1921P
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