Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50041996'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50041996 (CHEMBL3359570) Show SMILES Cl.CN1CCCN(CC1)c1ccc(cc1)C(=O)Nc1c(O)cccc1C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C26H27ClN4O3/c1-30-14-3-15-31(17-16-30)21-12-6-18(7-13-21)25(33)29-24-22(4-2-5-23(24)32)26(34)28-20-10-8-19(27)9-11-20/h2,4-13,32H,3,14-17H2,1H3,(H,28,34)(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate reader				Bioorg Med Chem 23: 277-89 (2015) Article DOI: 10.1016/j.bmc.2014.11.042 BindingDB Entry DOI: 10.7270/Q2P55Q4X
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