Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50074118'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50074118 (CHEMBL3409883) Show SMILES COc1ccc(NC(=O)C(=O)Nc2cccc(Cl)c2)c(c1)C(=O)Nc1ccc(cc1)N1CCOCC1=O Show InChI InChI=1S/C26H23ClN4O6/c1-36-20-9-10-22(30-26(35)25(34)29-18-4-2-3-16(27)13-18)21(14-20)24(33)28-17-5-7-19(8-6-17)31-11-12-37-15-23(31)32/h2-10,13-14H,11-12,15H2,1H3,(H,28,33)(H,29,34)(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	621	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human factor 10a using acromogenic substrate S-2222 preincubated for 30 mins before substrate addition measured after 20 mins by spectr...				Eur J Med Chem 95: 388-99 (2015) Article DOI: 10.1016/j.ejmech.2015.03.052 BindingDB Entry DOI: 10.7270/Q29G5PH4
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