Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50443851'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50443851 (CHEMBL3091521) Show SMILES [#6]-[#6]-c1c(cccc1S(=O)(=O)[#7]-[#6@@H](-[#6]-[#7]-[#6](=O)-c1csc(Cl)c1)-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](/F)F)-c1ccccn1 |r| Show InChI InChI=1S/C27H27ClF2N4O4S2/c1-2-19-20(21-7-3-4-11-31-21)6-5-8-23(19)40(37,38)33-22(15-32-26(35)18-14-24(28)39-16-18)27(36)34-12-9-17(10-13-34)25(29)30/h3-8,11,14,16,22,33H,2,9-10,12-13,15H2,1H3,(H,32,35)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis R&D Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assay				J Med Chem 56: 9441-56 (2014) Article DOI: 10.1021/jm4005835 BindingDB Entry DOI: 10.7270/Q20K2B0C
					More data for this Ligand-Target Pair