Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM170705'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM170705 (US9085555, 133) Show SMILES COC(=O)COc1ccc2n(cc(NC(=O)N3C4CC4C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1)C(N)=O |r| Show InChI InChI=1S/C26H25ClFN5O6/c1-38-22(34)12-39-15-5-6-19-16(9-15)18(11-32(19)25(29)36)31-26(37)33-20-7-14(20)8-21(33)24(35)30-10-13-3-2-4-17(27)23(13)28/h2-6,9,11,14,20-21H,7-8,10,12H2,1H3,(H2,29,36)(H,30,35)(H,31,37)/t14?,20?,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	25
NOVARTIS AG US Patent					Assay Description Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...				US Patent US9085555 (2015) BindingDB Entry DOI: 10.7270/Q2RN36MP
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