Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Complement factor D' and Ligand = 'BDBM170870'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM170870 (US9085555, 298) Show SMILES COc1ccc2n(cc(NC(=O)N3C[C@H](F)C[C@H]3C(=O)Nc3cccc(OC(F)(F)F)c3F)c2c1)C(N)=O |r| Show InChI InChI=1S/C23H20F5N5O5/c1-37-12-5-6-16-13(8-12)15(10-32(16)21(29)35)31-22(36)33-9-11(24)7-17(33)20(34)30-14-3-2-4-18(19(14)25)38-23(26,27)28/h2-6,8,10-11,17H,7,9H2,1H3,(H2,29,35)(H,30,34)(H,31,36)/t11-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	25
NOVARTIS AG US Patent					Assay Description Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...				US Patent US9085555 (2015) BindingDB Entry DOI: 10.7270/Q2RN36MP
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