Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50149672'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50149672 (CHEMBL184850 | [3-(5-Dimethylamino-3-methyl-pyridi...) Show SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ncc(cc1C)N(C)C |(3.65,5.88,;4.24,4.45,;3.3,3.22,;3.9,1.8,;5.42,1.61,;6.01,.19,;7.55,-.03,;2.95,.58,;3.54,-.84,;2.6,-2.06,;3.18,-3.47,;1.08,-1.85,;.5,-.43,;-.95,.09,;-.91,1.61,;-2.13,2.55,;.57,2.06,;1.45,.77,;-2.34,-.59,;-2.34,-2.15,;-3.68,-2.9,;-5.01,-2.15,;-5.01,-.59,;-3.68,.19,;-3.69,1.72,;-6.35,-2.9,;-7.69,-2.15,;-6.35,-4.46,)| Show InChI InChI=1S/C22H32N6/c1-8-10-27(11-9-2)19-13-16(4)24-22-20(17(5)25-28(19)22)21-15(3)12-18(14-23-21)26(6)7/h12-14H,8-11H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor				J Med Chem 47: 4787-98 (2004) Article DOI: 10.1021/jm040058e BindingDB Entry DOI: 10.7270/Q2N29WDR
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50149672 (CHEMBL184850 | [3-(5-Dimethylamino-3-methyl-pyridi...) Show SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ncc(cc1C)N(C)C |(3.65,5.88,;4.24,4.45,;3.3,3.22,;3.9,1.8,;5.42,1.61,;6.01,.19,;7.55,-.03,;2.95,.58,;3.54,-.84,;2.6,-2.06,;3.18,-3.47,;1.08,-1.85,;.5,-.43,;-.95,.09,;-.91,1.61,;-2.13,2.55,;.57,2.06,;1.45,.77,;-2.34,-.59,;-2.34,-2.15,;-3.68,-2.9,;-5.01,-2.15,;-5.01,-.59,;-3.68,.19,;-3.69,1.72,;-6.35,-2.9,;-7.69,-2.15,;-6.35,-4.46,)| Show InChI InChI=1S/C22H32N6/c1-8-10-27(11-9-2)19-13-16(4)24-22-20(17(5)25-28(19)22)21-15(3)12-18(14-23-21)26(6)7/h12-14H,8-11H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity for recombinant human CRF1 receptor				Bioorg Med Chem Lett 14: 3943-7 (2004) Article DOI: 10.1016/j.bmcl.2004.05.056 BindingDB Entry DOI: 10.7270/Q2KK9B7F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50149672 (CHEMBL184850 | [3-(5-Dimethylamino-3-methyl-pyridi...) Show SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ncc(cc1C)N(C)C |(3.65,5.88,;4.24,4.45,;3.3,3.22,;3.9,1.8,;5.42,1.61,;6.01,.19,;7.55,-.03,;2.95,.58,;3.54,-.84,;2.6,-2.06,;3.18,-3.47,;1.08,-1.85,;.5,-.43,;-.95,.09,;-.91,1.61,;-2.13,2.55,;.57,2.06,;1.45,.77,;-2.34,-.59,;-2.34,-2.15,;-3.68,-2.9,;-5.01,-2.15,;-5.01,-.59,;-3.68,.19,;-3.69,1.72,;-6.35,-2.9,;-7.69,-2.15,;-6.35,-4.46,)| Show InChI InChI=1S/C22H32N6/c1-8-10-27(11-9-2)19-13-16(4)24-22-20(17(5)25-28(19)22)21-15(3)12-18(14-23-21)26(6)7/h12-14H,8-11H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of CRF-stimulated cAMP production in cells expressing CRF1 receptor				Bioorg Med Chem Lett 14: 3943-7 (2004) Article DOI: 10.1016/j.bmcl.2004.05.056 BindingDB Entry DOI: 10.7270/Q2KK9B7F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50149672 (CHEMBL184850 | [3-(5-Dimethylamino-3-methyl-pyridi...) Show SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ncc(cc1C)N(C)C |(3.65,5.88,;4.24,4.45,;3.3,3.22,;3.9,1.8,;5.42,1.61,;6.01,.19,;7.55,-.03,;2.95,.58,;3.54,-.84,;2.6,-2.06,;3.18,-3.47,;1.08,-1.85,;.5,-.43,;-.95,.09,;-.91,1.61,;-2.13,2.55,;.57,2.06,;1.45,.77,;-2.34,-.59,;-2.34,-2.15,;-3.68,-2.9,;-5.01,-2.15,;-5.01,-.59,;-3.68,.19,;-3.69,1.72,;-6.35,-2.9,;-7.69,-2.15,;-6.35,-4.46,)| Show InChI InChI=1S/C22H32N6/c1-8-10-27(11-9-2)19-13-16(4)24-22-20(17(5)25-28(19)22)21-15(3)12-18(14-23-21)26(6)7/h12-14H,8-11H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor				J Med Chem 47: 4787-98 (2004) Article DOI: 10.1021/jm040058e BindingDB Entry DOI: 10.7270/Q2N29WDR
					More data for this Ligand-Target Pair