Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50152160'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50152160 (CHEMBL186592 | [3-(6-Dimethylamino-4-methyl-pyridi...) Show SMILES CCN(Cc1ccccc1F)c1cc(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C |(5.85,1.49,;4.82,.34,;3.32,.67,;2.84,2.12,;3.85,3.28,;5.36,2.95,;6.38,4.12,;5.9,5.56,;4.38,5.87,;3.36,4.73,;1.86,5.05,;2.29,-.49,;2.77,-1.93,;1.75,-3.08,;2.24,-4.54,;.26,-2.77,;-.23,-1.31,;-1.63,-.71,;-1.48,.84,;-2.63,1.86,;.02,1.16,;.79,-.17,;-2.96,-1.47,;-2.96,-3.01,;-4.29,-3.8,;-5.62,-3.01,;-5.62,-1.49,;-4.29,-.71,;-4.3,.84,;-6.96,-3.8,;-6.96,-5.32,;-8.29,-3.01,)| Show InChI InChI=1S/C25H29FN6/c1-7-31(15-19-10-8-9-11-21(19)26)23-13-17(3)28-25-24(18(4)29-32(23)25)20-14-27-22(30(5)6)12-16(20)2/h8-14H,7,15H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor				J Med Chem 47: 4787-98 (2004) Article DOI: 10.1021/jm040058e BindingDB Entry DOI: 10.7270/Q2N29WDR
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