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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50152161'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50152161
PNG
(CHEMBL364828 | [3-(6-Dimethylamino-2,4-dimethyl-py...)
Show SMILES CCCN(CCC)c1cc(C)nc2c(cnn12)-c1c(C)cc(nc1C)N(C)C |(3.92,5.72,;4.4,4.25,;3.38,3.12,;3.87,1.65,;5.38,1.35,;6.4,2.49,;7.89,2.19,;2.84,.51,;3.33,-.94,;2.31,-2.1,;2.79,-3.55,;.82,-1.77,;.33,-.33,;-1.07,.3,;-.93,1.84,;.59,2.16,;1.35,.82,;-2.39,-.47,;-3.73,.29,;-3.75,1.84,;-5.07,-.47,;-5.07,-2.03,;-3.73,-2.79,;-2.39,-2.03,;-1.07,-2.79,;-6.4,-2.79,;-7.75,-2.03,;-6.4,-4.33,)|
Show InChI InChI=1S/C22H32N6/c1-8-10-27(11-9-2)20-13-16(4)24-22-18(14-23-28(20)22)21-15(3)12-19(26(6)7)25-17(21)5/h12-14H,8-11H2,1-7H3
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Article
PubMed
 20n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor

J Med Chem 47: 4787-98 (2004)


Article DOI: 10.1021/jm040058e
BindingDB Entry DOI: 10.7270/Q2N29WDR
More data for this
Ligand-Target Pair