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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50152167'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50152167
PNG
(CHEMBL426260 | [3-(6-Dimethylamino-4-methyl-pyridi...)
Show SMILES CC(C)C(C)Nc1cc(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C |(6.4,3.7,;4.9,4.03,;4.42,5.48,;3.88,2.86,;2.37,3.17,;4.36,1.4,;3.34,.25,;3.81,-1.2,;2.79,-2.36,;3.28,-3.81,;1.29,-2.04,;.8,-.58,;-.6,.04,;-.44,1.58,;-1.6,2.59,;1.06,1.91,;1.83,.56,;-1.93,-.73,;-1.93,-2.29,;-3.26,-3.06,;-4.59,-2.29,;-4.59,-.75,;-3.26,.04,;-3.27,1.58,;-5.93,-3.06,;-5.93,-4.6,;-7.27,-2.29,)|
Show InChI InChI=1S/C21H30N6/c1-12(2)15(5)24-19-10-14(4)23-21-20(16(6)25-27(19)21)17-11-22-18(26(7)8)9-13(17)3/h9-12,15,24H,1-8H3
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Article
PubMed
 17n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor

J Med Chem 47: 4787-98 (2004)


Article DOI: 10.1021/jm040058e
BindingDB Entry DOI: 10.7270/Q2N29WDR
More data for this
Ligand-Target Pair