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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50152175'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50152175
PNG
(CHEMBL184284 | [3-(6-Dimethylamino-4-methyl-pyridi...)
Show SMILES CCC(COC)Nc1cc(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C |(1.7,4.5,;2.19,3.03,;3.69,2.72,;4.72,3.89,;6.23,3.56,;7.24,4.71,;4.18,1.25,;3.16,.11,;3.62,-1.34,;2.61,-2.5,;3.09,-3.95,;1.12,-2.18,;.63,-.73,;-.79,-.1,;-.62,1.44,;-1.79,2.44,;.89,1.77,;1.64,.41,;-2.1,-.87,;-2.1,-2.43,;-3.45,-3.2,;-4.78,-2.43,;-4.78,-.89,;-3.45,-.1,;-3.45,1.44,;-6.11,-3.2,;-7.44,-2.43,;-6.11,-4.74,)|
Show InChI InChI=1S/C21H30N6O/c1-8-16(12-28-7)24-19-10-14(3)23-21-20(15(4)25-27(19)21)17-11-22-18(26(5)6)9-13(17)2/h9-11,16,24H,8,12H2,1-7H3
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Article
PubMed
 260n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor

J Med Chem 47: 4787-98 (2004)


Article DOI: 10.1021/jm040058e
BindingDB Entry DOI: 10.7270/Q2N29WDR
More data for this
Ligand-Target Pair