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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50152184'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50152184
PNG
(CHEMBL189754 | [3-(6-Dimethylamino-4-methyl-pyridi...)
Show SMILES CC(C)CCC(C)Nc1cc(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C |(8.29,4.19,;6.77,4.5,;6.3,5.97,;5.75,3.35,;4.25,3.68,;3.23,2.51,;1.71,2.82,;3.71,1.05,;2.68,-.1,;3.16,-1.55,;2.13,-2.71,;2.62,-4.16,;.64,-2.39,;.15,-.93,;-1.25,-.31,;-1.1,1.23,;-2.26,2.24,;.4,1.56,;1.17,.2,;-2.58,-1.08,;-2.58,-2.64,;-3.91,-3.41,;-5.24,-2.64,;-5.24,-1.1,;-3.91,-.31,;-3.92,1.23,;-6.58,-3.41,;-6.58,-4.95,;-7.93,-2.64,)|
Show InChI InChI=1S/C23H34N6/c1-14(2)9-10-16(4)25-21-12-17(5)26-23-22(18(6)27-29(21)23)19-13-24-20(28(7)8)11-15(19)3/h11-14,16,25H,9-10H2,1-8H3
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Article
PubMed
 13n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor

J Med Chem 47: 4787-98 (2004)


Article DOI: 10.1021/jm040058e
BindingDB Entry DOI: 10.7270/Q2N29WDR
More data for this
Ligand-Target Pair