Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50152187'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50152187 (CHEMBL363269 | [3-(6-Dimethylamino-4-methyl-pyridi...) Show SMILES CCCN(Cc1ccc2ccccc2c1)c1cc(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C |(6.09,-2.02,;4.59,-1.71,;4.1,-.26,;2.6,.06,;2.11,1.54,;3.13,2.68,;4.64,2.36,;5.67,3.52,;5.19,4.98,;6.2,6.14,;5.71,7.58,;4.19,7.89,;3.16,6.75,;3.66,5.3,;2.64,4.15,;1.57,-1.08,;2.04,-2.53,;1.01,-3.7,;1.5,-5.15,;-.49,-3.39,;-.97,-1.93,;-2.38,-1.31,;-2.22,.23,;-3.38,1.25,;-.72,.56,;.05,-.78,;-3.71,-2.08,;-3.71,-3.63,;-5.05,-4.4,;-6.38,-3.63,;-6.38,-2.09,;-5.05,-1.31,;-5.05,.23,;-7.72,-4.4,;-9.06,-3.63,;-7.72,-5.95,)| Show InChI InChI=1S/C30H34N6/c1-7-14-35(19-23-12-13-24-10-8-9-11-25(24)17-23)28-16-21(3)32-30-29(22(4)33-36(28)30)26-18-31-27(34(5)6)15-20(26)2/h8-13,15-18H,7,14,19H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptor				J Med Chem 47: 4787-98 (2004) Article DOI: 10.1021/jm040058e BindingDB Entry DOI: 10.7270/Q2N29WDR
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