Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50169583'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50169583 (2-Ethyl-7-(2,4,6-trimethyl-phenyl)-6,7-dihydro-5H-...) Show SMILES CCc1nc2N(CCn2c1C(=O)NN1CCN(CC1)c1ccccc1F)c1c(C)cc(C)cc1C Show InChI InChI=1S/C27H33FN6O/c1-5-22-25(26(35)30-32-12-10-31(11-13-32)23-9-7-6-8-21(23)28)34-15-14-33(27(34)29-22)24-19(3)16-18(2)17-20(24)4/h6-9,16-17H,5,10-15H2,1-4H3,(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr-o- CRF from human corticotropin releasing factor receptor 1 expressed in IMR-32 cells				Bioorg Med Chem Lett 15: 3870-3 (2005) Article DOI: 10.1016/j.bmcl.2005.05.117 BindingDB Entry DOI: 10.7270/Q269733T
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