Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50203611'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50203611 (CHEMBL393044 | [8-(2-chloro-4,6-dimethyl-phenyl)-2...) Show SMILES CCCN(CC1CCC1)Cc1c(C)nc2n(-c3c(C)cc(C)cc3Cl)c3ncccc3n12 |(16.3,-32.74,;17.29,-33.92,;18.81,-33.65,;19.8,-34.83,;21.32,-34.56,;21.84,-33.11,;23.23,-32.46,;22.58,-31.07,;21.19,-31.72,;19.28,-36.27,;20.27,-37.45,;19.9,-38.95,;18.47,-39.53,;21.21,-39.76,;22.39,-38.77,;23.93,-38.66,;24.92,-39.84,;26.42,-39.57,;26.94,-38.13,;27.41,-40.75,;26.89,-42.2,;27.88,-43.38,;25.37,-42.47,;24.38,-41.29,;22.86,-41.55,;24.3,-37.18,;25.67,-36.45,;25.73,-34.9,;24.41,-34.08,;23.04,-34.81,;22.99,-36.35,;21.81,-37.34,)| Show InChI InChI=1S/C26H32ClN5/c1-5-12-30(15-20-8-6-9-20)16-23-19(4)29-26-31(23)22-10-7-11-28-25(22)32(26)24-18(3)13-17(2)14-21(24)27/h7,10-11,13-14,20H,5-6,8-9,12,15-16H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-o-CRF from CRF1 receptor expressed in IMR32 cells assessed as inhibition of CRF stimulated cAMP production				Bioorg Med Chem Lett 17: 2026-30 (2007) Article DOI: 10.1016/j.bmcl.2007.01.008 BindingDB Entry DOI: 10.7270/Q21R6Q5Q
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