Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50300139'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50300139 ((S)-4-(1-Cyclopropyl-2-methoxyethyl)-6-(6-methoxy-...) Show SMILES COC[C@H](C1CC1)n1cc(nc(Nc2cc(C)c(OC)nc2C)c1=O)C#N |r| Show InChI InChI=1S/C19H23N5O3/c1-11-7-15(12(2)21-18(11)27-4)23-17-19(25)24(9-14(8-20)22-17)16(10-26-3)13-5-6-13/h7,9,13,16H,5-6,10H2,1-4H3,(H,22,23)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-o-CRF from CRF1 receptor in rat frontal cortex homogenate by binding titration assay				J Med Chem 52: 7653-68 (2009) Article DOI: 10.1021/jm900716v BindingDB Entry DOI: 10.7270/Q2CN740W
					More data for this Ligand-Target Pair