Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50413233'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50413233 (CHEMBL458169) Show SMILES Cc1cc(-n2ccc(n2)-c2nccs2)c2nc(n(-c3ccc(cc3C(F)(F)F)C(F)(F)F)c2n1)C(F)(F)F |(10.43,-27.88,;11.76,-27.11,;11.77,-25.57,;13.09,-24.79,;13.09,-23.26,;11.84,-22.35,;12.31,-20.89,;13.85,-20.88,;14.33,-22.35,;14.76,-19.64,;16.3,-19.63,;16.77,-18.17,;15.53,-17.28,;14.28,-18.18,;14.43,-25.56,;15.9,-25.08,;16.82,-26.33,;15.9,-27.59,;15.44,-29.06,;13.93,-29.38,;13.46,-30.85,;14.5,-31.99,;16.01,-31.65,;16.47,-30.19,;17.98,-29.86,;19.5,-29.6,;17.68,-28.34,;18.26,-31.37,;14.03,-33.46,;15.49,-33.96,;12.58,-32.95,;13.57,-34.92,;14.43,-27.11,;13.1,-27.88,;18.36,-26.33,;19.9,-26.33,;18.36,-27.87,;18.36,-24.79,)| Show InChI InChI=1S/C22H11F9N6S/c1-10-8-15(36-6-4-13(35-36)18-32-5-7-38-18)16-17(33-10)37(19(34-16)22(29,30)31)14-3-2-11(20(23,24)25)9-12(14)21(26,27)28/h2-9H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of [125I]sauvagine from human recombinant CRF1 receptor expressed in CHO cells by SPA				J Med Chem 51: 7273-86 (2009) Article DOI: 10.1021/jm800743q BindingDB Entry DOI: 10.7270/Q2TT4S62
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