Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Cyclic GMP-AMP synthase' and Ligand = 'BDBM50582696'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclic GMP-AMP synthase (Homo sapiens)	BDBM50582696 (CHEMBL5076595) Show SMILES COC(=O)c1nc(N)nc(Nc2cc(F)c(I)c(F)c2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human cGAS assessed as reduction in 2,3-cGAMP synthesis by measuring ATP consumption incubated for 20 mins by Kinase Glo luminescence a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00398 BindingDB Entry DOI: 10.7270/Q2RF5ZXH
					More data for this Ligand-Target Pair
Cyclic GMP-AMP synthase (Homo sapiens)	BDBM50582696 (CHEMBL5076595) Show SMILES COC(=O)c1nc(N)nc(Nc2cc(F)c(I)c(F)c2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114645 BindingDB Entry DOI: 10.7270/Q2SQ94GB
					More data for this Ligand-Target Pair
Cyclic GMP-AMP synthase (Homo sapiens)	BDBM50582696 (CHEMBL5076595) Show SMILES COC(=O)c1nc(N)nc(Nc2cc(F)c(I)c(F)c2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2021.128101 BindingDB Entry DOI: 10.7270/Q2W95F4V
					More data for this Ligand-Target Pair