Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclic GMP-AMP synthase [155-522]' and Ligand = 'BDBM457582'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclic GMP-AMP synthase [155-522] (Homo sapiens (Human))	BDBM457582 (US10738056, Compound D1027) Show SMILES COC1CCCN(C1)c1nnc(o1)-c1c(C)[nH]c2c(c(nn2c1=O)C(F)(F)F)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<20	n/a	n/a	n/a	n/a	n/a	n/a
Aduro BioTech Inc. US Patent					Assay Description Protein was expressed and purified from E. coli BL21 DE3 Rosetta 2 (EMD Millipore) cells using standard techniques. Cells were grown in 2x yeast extr...				US Patent US10738056 (2020) BindingDB Entry DOI: 10.7270/Q28G8PR3
					More data for this Ligand-Target Pair