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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-A2 [171-432]/Cyclin-dependent kinase 2' and Ligand = 'BDBM5583'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2


(Homo sapiens (Human))		BDBM5583
PNG
(6-(cyclohexylmethoxy)-5-[(1E)-(methoxyimino)methyl...)
Show SMILES CO\N=C\c1c(N)nc(N)nc1OCC1CCCCC1
Show InChI InChI=1S/C13H21N5O2/c1-19-16-7-10-11(14)17-13(15)18-12(10)20-8-9-5-3-2-4-6-9/h7,9H,2-6,8H2,1H3,(H4,14,15,17,18)/b16-7+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



University of Newcastle



Assay Description
The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...

Bioorg Med Chem Lett 13: 217-22 (2003)


Article DOI: 10.1016/s0960-894x(02)00884-3
BindingDB Entry DOI: 10.7270/Q2W09433
More data for this
Ligand-Target Pair