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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cyclin-C/Cyclin-dependent kinase 19' and Ligand = 'BDBM50529873'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-C/Cyclin-dependent kinase 19


(Homo sapiens (Human))
BDBM50529873
PNG
(CHEMBL4552616)
Show SMILES Cc1ncccc1Oc1sc(C(N)=O)c2CCc3cnn(C)c3-c12
Show InChI InChI=1S/C17H16N4O2S/c1-9-12(4-3-7-19-9)23-17-13-11(15(24-17)16(18)22)6-5-10-8-20-21(2)14(10)13/h3-4,7-8H,5-6H2,1-2H3,(H2,18,22)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.90n/an/an/an/an/an/a



Shaoxing University

Curated by ChEMBL


Assay Description
Displacement of Kinase tracer 236 from GST-fused CDK19/cyclin C (unknown origin) after 60 mins by TR-FRET assay


Eur J Med Chem 164: 77-91 (2019)


Article DOI: 10.1016/j.ejmech.2018.11.076
BindingDB Entry DOI: 10.7270/Q25142PT
More data for this
Ligand-Target Pair
Cyclin-C/Cyclin-dependent kinase 19


(Homo sapiens (Human))
BDBM50529873
PNG
(CHEMBL4552616)
Show SMILES Cc1ncccc1Oc1sc(C(N)=O)c2CCc3cnn(C)c3-c12
Show InChI InChI=1S/C17H16N4O2S/c1-9-12(4-3-7-19-9)23-17-13-11(15(24-17)16(18)22)6-5-10-8-20-21(2)14(10)13/h3-4,7-8H,5-6H2,1-2H3,(H2,18,22)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.90n/an/an/an/an/an/a



Shaoxing University

Curated by ChEMBL


Assay Description
Displacement of Kinase tracer 236 from GST-fused CDK19/cyclin C (unknown origin) after 60 mins by TR-FRET assay


Eur J Med Chem 164: 77-91 (2019)


Article DOI: 10.1016/j.ejmech.2018.11.076
BindingDB Entry DOI: 10.7270/Q25142PT
More data for this
Ligand-Target Pair