Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cyclin-K/Cyclin-dependent kinase 12' and Ligand = 'BDBM479015'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-K/Cyclin-dependent kinase 12 (Homo sapiens (Human))	BDBM479015 ((R)-N-(4-(3-((5-chloro-4- methylpyridin-2- yl)amin...) Show SMILES Cc1cc(N[C@@H]2CCN(C2)C(=O)c2ccc(NC(=O)C=C)cc2)ncc1Cl |r| Show InChI InChI=1S/C20H21ClN4O2/c1-3-19(26)24-15-6-4-14(5-7-15)20(27)25-9-8-16(12-25)23-18-10-13(2)17(21)11-22-18/h3-7,10-11,16H,1,8-9,12H2,2H3,(H,22,23)(H,24,26)/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...				Citation and Details BindingDB Entry DOI: 10.7270/Q2R78JFB
					More data for this Ligand-Target Pair
Cyclin-K/Cyclin-dependent kinase 12 (Homo sapiens (Human))	BDBM479015 ((R)-N-(4-(3-((5-chloro-4- methylpyridin-2- yl)amin...) Show SMILES Cc1cc(N[C@@H]2CCN(C2)C(=O)c2ccc(NC(=O)C=C)cc2)ncc1Cl |r| Show InChI InChI=1S/C20H21ClN4O2/c1-3-19(26)24-15-6-4-14(5-7-15)20(27)25-9-8-16(12-25)23-18-10-13(2)17(21)11-22-18/h3-7,10-11,16H,1,8-9,12H2,2H3,(H,22,23)(H,24,26)/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...				Citation and Details BindingDB Entry DOI: 10.7270/Q2R78JFB
					More data for this Ligand-Target Pair