Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cyclin-K/Cyclin-dependent kinase 12' and Ligand = 'BDBM479018'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-K/Cyclin-dependent kinase 12 (Homo sapiens (Human))	BDBM479018 ((R)-N-(4-(3-((5- cyclopropylpyrimidin-2- yl)amino)...) Show SMILES C=CC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc(cn1)C1CC1 |r| Show InChI InChI=1S/C21H23N5O2/c1-2-19(27)24-17-7-5-15(6-8-17)20(28)26-10-9-18(13-26)25-21-22-11-16(12-23-21)14-3-4-14/h2,5-8,11-12,14,18H,1,3-4,9-10,13H2,(H,24,27)(H,22,23,25)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...				Citation and Details BindingDB Entry DOI: 10.7270/Q2R78JFB
					More data for this Ligand-Target Pair
Cyclin-K/Cyclin-dependent kinase 12 (Homo sapiens (Human))	BDBM479018 ((R)-N-(4-(3-((5- cyclopropylpyrimidin-2- yl)amino)...) Show SMILES C=CC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc(cn1)C1CC1 |r| Show InChI InChI=1S/C21H23N5O2/c1-2-19(27)24-17-7-5-15(6-8-17)20(28)26-10-9-18(13-26)25-21-22-11-16(12-23-21)14-3-4-14/h2,5-8,11-12,14,18H,1,3-4,9-10,13H2,(H,24,27)(H,22,23,25)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The IC50 profile of test compounds was determined using three protein kinases. IC50 values were measured by testing 10 concentrations (1×10−04M...				Citation and Details BindingDB Entry DOI: 10.7270/Q2R78JFB
					More data for this Ligand-Target Pair