Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1' and Ligand = 'BDBM59232'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM59232 (Pyrazolopyrimidone analog, RGB-310595) Show SMILES COc1ccc(Cc2nc3n[nH]c(C(C)C)c3c(=O)[nH]2)cc1 Show InChI InChI=1S/C16H18N4O2/c1-9(2)14-13-15(20-19-14)17-12(18-16(13)21)8-10-4-6-11(22-3)7-5-10/h4-7,9H,8H2,1-3H3,(H2,17,18,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GPC Biotech, Inc.					Assay Description Inhibition of HCT116 cell proliferation after 72hr of incubation with compounds was determined by SRB Assay.				Chem Biol 12: 1103-15 (2005) Article DOI: 10.1016/j.chembiol.2005.08.008 BindingDB Entry DOI: 10.7270/Q28W3BR6
					More data for this Ligand-Target Pair