Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 1/G1/S-specific cyclin-D3 (Homo sapiens (Human)) | BDBM50110183 (Abemaciclib | LY-2835219 | US10626107, Example LY2...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 5.08 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase 1/G1/S-specific cyclin-D3 (Homo sapiens (Human)) | BDBM50110183 (Abemaciclib | LY-2835219 | US10626107, Example LY2...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 5.08 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase 1/G1/S-specific cyclin-D3 (Homo sapiens (Human)) | BDBM50110183 (Abemaciclib | LY-2835219 | US10626107, Example LY2...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 5.08 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/... | Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase 1/G1/S-specific cyclin-D3 (Homo sapiens (Human)) | BDBM50110183 (Abemaciclib | LY-2835219 | US10626107, Example LY2...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of recombinant human full length CDK1/Cyclin D3 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 min... | Bioorg Med Chem Lett 28: 974-978 (2018) Article DOI: 10.1016/j.bmcl.2017.12.068 BindingDB Entry DOI: 10.7270/Q2BC4236 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |