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Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B' and Ligand = 'BDBM5578'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B


(Marthasterias glacialis (starfish))		BDBM5578
PNG
(benzyl N-[2-amino-6-(cyclohexylmethoxy)-5-nitrosop...)
Show SMILES Nc1nc(NC(=O)OCc2ccccc2)c(N=O)c(OCC2CCCCC2)n1
Show InChI InChI=1S/C19H23N5O4/c20-18-21-16(22-19(25)28-12-14-9-5-2-6-10-14)15(24-26)17(23-18)27-11-13-7-3-1-4-8-13/h2,5-6,9-10,13H,1,3-4,7-8,11-12H2,(H3,20,21,22,23,25)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/an/an/an/a7.530



University of Newcastle



Assay Description
The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...

Bioorg Med Chem Lett 13: 217-22 (2003)


Article DOI: 10.1016/s0960-894x(02)00884-3
BindingDB Entry DOI: 10.7270/Q2W09433
More data for this
Ligand-Target Pair