Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 1' and Ligand = 'BDBM148287'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM148287 (US8962630, 101) Show SMILES COC(=O)C(C)N1CCN(CC1)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)nc1 Show InChI InChI=1S/C27H36N8O3/c1-18(26(37)38-4)33-11-13-34(14-12-33)21-9-10-23(28-17-21)30-27-29-16-19-15-22(25(36)32(2)3)35(24(19)31-27)20-7-5-6-8-20/h9-10,15-18,20H,5-8,11-14H2,1-4H3,(H,28,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ...				US Patent US8962630 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4H6C
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