Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 1' and Ligand = 'BDBM50212014'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50212014 (4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-(2-ethyl-...) Show SMILES CCc1nccn1CCc1ccc(Nc2ncc(C#N)c(n2)-c2ccc(cc2)C(C)(C)N)cc1 Show InChI InChI=1S/C27H29N7/c1-4-24-30-14-16-34(24)15-13-19-5-11-23(12-6-19)32-26-31-18-21(17-28)25(33-26)20-7-9-22(10-8-20)27(2,3)29/h5-12,14,16,18H,4,13,15,29H2,1-3H3,(H,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of CDK1 activity				Bioorg Med Chem Lett 17: 3266-70 (2007) Article DOI: 10.1016/j.bmcl.2007.04.021 BindingDB Entry DOI: 10.7270/Q2GQ6XFG
					More data for this Ligand-Target Pair