Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 2' and Ligand = 'BDBM105244'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM105244 (US8580782, 18) Show SMILES CN1CCN(CC1)c1cc(NCc2cccnc2)n2ncc(Br)c2n1 Show InChI InChI=1S/C17H20BrN7/c1-23-5-7-24(8-6-23)16-9-15(20-11-13-3-2-4-19-10-13)25-17(22-16)14(18)12-21-25/h2-4,9-10,12,20H,5-8,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	8.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).				US Patent US8580782 (2013) BindingDB Entry DOI: 10.7270/Q2VM49WG
					More data for this Ligand-Target Pair