Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4' and Ligand = 'BDBM50293160'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM50293160 (4-(6-isopropoxypyrazolo[1,5-b]pyridazin-3-yl)-N-(4...) Show SMILES CC(C)Oc1ccc2c(cnn2n1)-c1ccnc(Nc2ccc(cc2)N2CCN(C)CC2)n1 Show InChI InChI=1S/C24H28N8O/c1-17(2)33-23-9-8-22-20(16-26-32(22)29-23)21-10-11-25-24(28-21)27-18-4-6-19(7-5-18)31-14-12-30(3)13-15-31/h4-11,16-17H,12-15H2,1-3H3,(H,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CDK4 by radioactive glutathione plate-binding assay				Bioorg Med Chem Lett 18: 5758-62 (2009) Article DOI: 10.1016/j.bmcl.2008.09.069 BindingDB Entry DOI: 10.7270/Q2J67GZN
					More data for this Ligand-Target Pair