Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 5 activator 1' and Ligand = 'BDBM50488801'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50488801 (CHEMBL2295939) Show SMILES CC(C)C(O)Nc1nc(Nc2cccc(c2)-c2ncccn2)c2ncn(C(C)C)c2n1 Show InChI InChI=1S/C22H26N8O/c1-13(2)21(31)29-22-27-19(17-20(28-22)30(12-25-17)14(3)4)26-16-8-5-7-15(11-16)18-23-9-6-10-24-18/h5-14,21,31H,1-4H3,(H2,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [gamma33P]ATP as substrate after 30 min by scintillation counting				Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F
					More data for this Ligand-Target Pair