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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 6/G1/S-specific cyclin-D3' and Ligand = 'BDBM50501579'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3


(Homo sapiens (Human))		BDBM50501579
PNG
(CHEMBL4089056)
Show SMILES Cc1nc(NC2CCCC2)sc1-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F
Show InChI InChI=1S/C22H27FN8S/c1-14-20(32-22(27-14)28-15-4-2-3-5-15)19-17(23)13-26-21(30-19)29-18-7-6-16(12-25-18)31-10-8-24-9-11-31/h6-7,12-13,15,24H,2-5,8-11H2,1H3,(H,27,28)(H,25,26,29,30)
PDB

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PC cid
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Article
PubMed
 7n/an/an/an/an/an/an/an/a



University of South Australia

Curated by ChEMBL


Assay Description
Inhibition of CDK6/cyclin D3 (unknown origin) in presence of [gamma-33P]-ATP by KINOMEscan assay

J Med Chem 60: 1892-1915 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01670
BindingDB Entry DOI: 10.7270/Q29Z97XG
More data for this
Ligand-Target Pair