Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM50553499![]() (CHEMBL4754493) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Ability to displace [3H]glycine from strychnine-insensitive glycine receptor | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM50553499![]() (CHEMBL4754493) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to wild-type human full length CDK7 (M1 to L344 residues) expressed in mammalian expression system by Kinomescan method | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00744 BindingDB Entry DOI: 10.7270/Q2FB56K3 | |||||||||||
More data for this Ligand-Target Pair |