Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 9' and Ligand = 'BDBM307715'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM307715 ( trans-4-({5-chloro-4-[1-(3-fluorobenzyl)-1H-benzi...) Show SMILES O[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1ccc2ncn(Cc3cccc(F)c3)c2c1 |r,wU:1.0,wD:4.7,(14.26,11.31,;12.93,10.54,;12.93,9,;11.59,8.23,;10.26,9,;10.26,10.54,;11.59,11.31,;8.92,8.23,;8.92,6.69,;7.59,5.92,;7.59,4.38,;8.92,3.61,;8.92,2.07,;10.26,4.38,;10.26,5.92,;6.26,3.61,;6.26,2.07,;4.92,1.3,;3.59,2.07,;2.13,1.6,;1.22,2.84,;2.13,4.09,;1.65,5.55,;2.68,6.7,;4.19,6.38,;5.22,7.52,;4.74,8.99,;3.23,9.31,;2.76,10.77,;2.2,8.16,;3.59,3.61,;4.92,4.38,)| Show InChI InChI=1S/C25H24ClFN4O/c26-22-13-28-25(30-19-5-7-20(32)8-6-19)12-21(22)17-4-9-23-24(11-17)31(15-29-23)14-16-2-1-3-18(27)10-16/h1-4,9-13,15,19-20,32H,5-8,14H2,(H,28,30)/t19-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9650358 (2017) BindingDB Entry DOI: 10.7270/Q2057J0M
					More data for this Ligand-Target Pair