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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cysteine protease' and Ligand = 'BDBM50263623'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cysteine protease


(Trypanosoma brucei rhodesiense)		BDBM50263623
PNG
(CHEMBL4093444)
Show SMILES Cn1ncc(n1)C(=O)N[C@@H](Cc1ccc(OC(F)(F)F)c(Cl)c1)C(=O)NC1(CC1)C#N |r|
Show InChI InChI=1S/C18H16ClF3N6O3/c1-28-24-8-13(27-28)15(29)25-12(16(30)26-17(9-23)4-5-17)7-10-2-3-14(11(19)6-10)31-18(20,21)22/h2-3,6,8,12H,4-5,7H2,1H3,(H,25,29)(H,26,30)/t12-/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
 23n/an/an/an/an/an/an/an/a



Laboratorium für Organische Chemie , ETH Zurich , Vladimir-Prelog-Weg 3 , 8093 Zürich , Switzerland.

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric method

J Med Chem 61: 3370-3388 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01870
BindingDB Entry DOI: 10.7270/Q2MC92GH
More data for this
Ligand-Target Pair