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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cysteine protease' and Ligand = 'BDBM50263649'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cysteine protease


(Trypanosoma brucei rhodesiense)		BDBM50263649
PNG
(CHEMBL4078079)
Show SMILES FC1(F)CC(C1)n1ncc(n1)C(=O)N[C@@H](Cc1ccc(Cl)c(Cl)c1)C(=O)NC1(CC1)C#N |r|
Show InChI InChI=1S/C20H18Cl2F2N6O2/c21-13-2-1-11(5-14(13)22)6-15(18(32)28-19(10-25)3-4-19)27-17(31)16-9-26-30(29-16)12-7-20(23,24)8-12/h1-2,5,9,12,15H,3-4,6-8H2,(H,27,31)(H,28,32)/t15-/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
 18n/an/an/an/an/an/an/an/a



Laboratorium für Organische Chemie , ETH Zurich , Vladimir-Prelog-Weg 3 , 8093 Zürich , Switzerland.

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric method

J Med Chem 61: 3370-3388 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01870
BindingDB Entry DOI: 10.7270/Q2MC92GH
More data for this
Ligand-Target Pair