Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cystic fibrosis transmembrane conductance regulator' and Ligand = 'BDBM50130986'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Rattus norvegicus)	BDBM50130986 (2-{3-[2-(3-Methoxy-benzyloxy)-phenyl]-isoxazol-5-y...) Show SMILES COc1cccc(COc2ccccc2-c2cc(CCO)on2)c1 Show InChI InChI=1S/C19H19NO4/c1-22-15-6-4-5-14(11-15)13-23-19-8-3-2-7-17(19)18-12-16(9-10-21)24-20-18/h2-8,11-12,21H,9-10,13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	1.77E+5	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Kd (half effective concentration) of compound against CFTR (cystic fibrosis transmembrane conductance regulator) in rat was determined				Bioorg Med Chem Lett 13: 2509-12 (2003) BindingDB Entry DOI: 10.7270/Q27D2TJS
					More data for this Ligand-Target Pair