Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B1, mitochondrial' and Ligand = 'BDBM232946'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM232946 (US9351973, 26 | US9844553, 26) Show SMILES Clc1cncc(c1)-c1nn2CCC(=O)Nc2c1C#N Show InChI InChI=1S/C12H8ClN5O/c13-8-3-7(5-15-6-8)11-9(4-14)12-16-10(19)1-2-18(12)17-11/h3,5-6H,1-2H2,(H,16,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Methods for V79-Human-CYP11B2 and V79-Human-CYP11B1 Assays: V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme...				US Patent US9844553 (2017) BindingDB Entry DOI: 10.7270/Q2J67K61
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM232946 (US9351973, 26 | US9844553, 26) Show SMILES Clc1cncc(c1)-c1nn2CCC(=O)Nc2c1C#N Show InChI InChI=1S/C12H8ClN5O/c13-8-3-7(5-15-6-8)11-9(4-14)12-16-10(19)1-2-18(12)17-11/h3,5-6H,1-2H2,(H,16,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp. US Patent					Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...				US Patent US9351973 (2016) BindingDB Entry DOI: 10.7270/Q2D799BC
					More data for this Ligand-Target Pair