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Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B1, mitochondrial' and Ligand = 'BDBM50341483'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cytochrome P450 11B1, mitochondrial


(Homo sapiens (Human))		BDBM50341483
PNG
(8-[5-(3-hydroxyphenyl)pyridin-3-yl]-1,2,5,6-tetrah...)
Show SMILES Oc1cccc(c1)-c1cncc(c1)-c1cc2CCN3c2c(CCC3=O)c1
Show InChI InChI=1S/C22H18N2O2/c25-20-3-1-2-14(11-20)18-10-19(13-23-12-18)17-8-15-4-5-21(26)24-7-6-16(9-17)22(15)24/h1-3,8-13,25H,4-7H2
PDB

KEGG

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DrugBank
antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 44n/an/an/an/an/an/a



Saarland University

Curated by ChEMBL


Assay Description
Inhibition of human CYP11B1 expressed in hamster V79 MZh cells assessed as conversion of [4-14C]-11-deoxycorticosterone substrate by HPTLC assay

J Med Chem 54: 2307-19 (2011)


Article DOI: 10.1021/jm101470k
BindingDB Entry DOI: 10.7270/Q2765FM6
More data for this
Ligand-Target Pair