Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B2, mitochondrial' and Ligand = 'BDBM232945'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM232945 (US9351973, 19 | US9844553, 19) Show SMILES Fc1cncc(c1)-c1nn2CCC(=O)Nc2c1C1CC1 Show InChI InChI=1S/C14H13FN4O/c15-10-5-9(6-16-7-10)13-12(8-1-2-8)14-17-11(20)3-4-19(14)18-13/h5-8H,1-4H2,(H,17,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Methods for V79-Human-CYP11B2 and V79-Human-CYP11B1 Assays: V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme...				US Patent US9844553 (2017) BindingDB Entry DOI: 10.7270/Q2J67K61
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM232945 (US9351973, 19 | US9844553, 19) Show SMILES Fc1cncc(c1)-c1nn2CCC(=O)Nc2c1C1CC1 Show InChI InChI=1S/C14H13FN4O/c15-10-5-9(6-16-7-10)13-12(8-1-2-8)14-17-11(20)3-4-19(14)18-13/h5-8H,1-4H2,(H,17,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp. US Patent					Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...				US Patent US9351973 (2016) BindingDB Entry DOI: 10.7270/Q2D799BC
					More data for this Ligand-Target Pair