Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B2, mitochondrial' and Ligand = 'BDBM280293'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM280293 (US10029993, Example 82) Show SMILES CN1CCNC(=O)[C@@]11CCC(CC1)NC(=O)CN1CCN(CC1)c1nncc(n1)-c1ccc(F)cc1 |r,wU:7.7,(12,1.93,;13.34,1.16,;14.67,1.93,;16,1.16,;16,-.38,;14.67,-1.15,;14.67,-2.69,;13.34,-.38,;13.34,-1.92,;12,-2.69,;10.67,-1.92,;10.67,-.38,;12,.39,;9.34,-2.69,;8,-1.92,;8,-.38,;6.67,-2.69,;5.33,-1.92,;4,-2.69,;2.67,-1.92,;2.67,-.38,;4,.38,;5.33,-.38,;1.33,.38,;1.33,1.92,;,2.69,;-1.33,1.92,;-1.33,.38,;,-.38,;-2.67,-.38,;-4,.38,;-5.33,-.38,;-5.33,-1.92,;-6.67,-2.69,;-4,-2.69,;-2.67,-1.92,)| Show InChI InChI=1S/C25H33FN8O2/c1-32-11-10-27-23(36)25(32)8-6-20(7-9-25)29-22(35)17-33-12-14-34(15-13-33)24-30-21(16-28-31-24)18-2-4-19(26)5-3-18/h2-5,16,20H,6-15,17H2,1H3,(H,27,36)(H,29,35)/t20?,25-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.4	25
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The pcDNA3.1-human CYP11B2 plasmid was transfected into a Chinese hamster lung fibroblast V79 cell line to produce a cell line stably expressing huma...				US Patent US10029993 (2018) BindingDB Entry DOI: 10.7270/Q2V40X6M
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