Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B2, mitochondrial' and Ligand = 'BDBM280305'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM280305 (US10029993, Example 154) Show SMILES Cc1nc[nH]c1CN1CCC(CC1)NC(=O)CN1CCN(CC1)c1nncc(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H32ClN9O/c1-18-23(28-17-27-18)15-33-8-6-21(7-9-33)30-24(36)16-34-10-12-35(13-11-34)25-31-22(14-29-32-25)19-2-4-20(26)5-3-19/h2-5,14,17,21H,6-13,15-16H2,1H3,(H,27,28)(H,30,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.4	25
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The pcDNA3.1-human CYP11B2 plasmid was transfected into a Chinese hamster lung fibroblast V79 cell line to produce a cell line stably expressing huma...				US Patent US10029993 (2018) BindingDB Entry DOI: 10.7270/Q2V40X6M
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