Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B2, mitochondrial' and Ligand = 'BDBM336516'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM336516 ((R)-1-(7-fluoro-5-(5- (1,1,1-trifluoro-2- hydroxyp...) Show SMILES CC(=O)N1CCc2cc(cc(F)c12)-c1cncc(c1)C(C)(O)C(F)(F)F Show InChI InChI=1S/C18H16F4N2O2/c1-10(25)24-4-3-11-5-12(7-15(19)16(11)24)13-6-14(9-23-8-13)17(2,26)18(20,21)22/h5-9,26H,3-4H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp; ElexoPharm GmbH US Patent					Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...				US Patent US9745282 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z66
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM336516 ((R)-1-(7-fluoro-5-(5- (1,1,1-trifluoro-2- hydroxyp...) Show SMILES CC(=O)N1CCc2cc(cc(F)c12)-c1cncc(c1)C(C)(O)C(F)(F)F Show InChI InChI=1S/C18H16F4N2O2/c1-10(25)24-4-3-11-5-12(7-15(19)16(11)24)13-6-14(9-23-8-13)17(2,26)18(20,21)22/h5-9,26H,3-4H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp; ElexoPharm GmbH US Patent					Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...				US Patent US9745282 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z66
					More data for this Ligand-Target Pair