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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B2, mitochondrial' and Ligand = 'BDBM351269'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))		BDBM351269
PNG
(CHEM-US-00080 | US9796702, 30)
Show SMILES CN1C(=O)CCc2c(Cl)c(ccc12)-c1n[nH]cc1CC1CCN(CC1)C(=O)c1ccncc1Cl
Show InChI InChI=1S/C25H25Cl2N5O2/c1-31-21-4-2-19(23(27)18(21)3-5-22(31)33)24-16(13-29-30-24)12-15-7-10-32(11-8-15)25(34)17-6-9-28-14-20(17)26/h2,4,6,9,13-15H,3,5,7-8,10-12H2,1H3,(H,29,30)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0190n/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...

US Patent US9796702 (2017)


BindingDB Entry DOI: 10.7270/Q2DB840G
More data for this
Ligand-Target Pair