Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B2, mitochondrial' and Ligand = 'BDBM351278'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM351278 (5-Chloro-6-[4-[(2-ethylsulfonyl-2-azaspiro[3.3]hep...) Show SMILES CCS(=O)(=O)N1CC2(CC(Cc3c[nH]nc3-c3ccc4N(C)C(=O)CCc4c3Cl)C2)C1 Show InChI InChI=1S/C22H27ClN4O3S/c1-3-31(29,30)27-12-22(13-27)9-14(10-22)8-15-11-24-25-21(15)17-4-6-18-16(20(17)23)5-7-19(28)26(18)2/h4,6,11,14H,3,5,7-10,12-13H2,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.00600	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9796702 (2017) BindingDB Entry DOI: 10.7270/Q2DB840G
					More data for this Ligand-Target Pair