Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B2, mitochondrial' and Ligand = 'BDBM351279'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM351279 (6-[4-[(2-Acetyl-2-azaspiro[3.3]heptan-6-yl)methyl]...) Show SMILES CN1C(=O)CCc2c(Cl)c(ccc12)-c1n[nH]cc1CC1CC2(C1)CN(C2)C(C)=O Show InChI InChI=1S/C22H25ClN4O2/c1-13(28)27-11-22(12-27)8-14(9-22)7-15-10-24-25-21(15)17-3-5-18-16(20(17)23)4-6-19(29)26(18)2/h3,5,10,14H,4,6-9,11-12H2,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0500	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9796702 (2017) BindingDB Entry DOI: 10.7270/Q2DB840G
					More data for this Ligand-Target Pair