Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B2, mitochondrial' and Ligand = 'BDBM50019887'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50019887 (CHEMBL3287179 | US9745282, 29) Show SMILES CCC(=O)N1CCc2cc(ccc12)-c1cncc2ccccc12 Show InChI InChI=1S/C20H18N2O/c1-2-20(23)22-10-9-15-11-14(7-8-19(15)22)18-13-21-12-16-5-3-4-6-17(16)18/h3-8,11-13H,2,9-10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp; ElexoPharm GmbH US Patent					Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...				US Patent US9745282 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z66
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50019887 (CHEMBL3287179 | US9745282, 29) Show SMILES CCC(=O)N1CCc2cc(ccc12)-c1cncc2ccccc12 Show InChI InChI=1S/C20H18N2O/c1-2-20(23)22-10-9-15-11-14(7-8-19(15)22)18-13-21-12-16-5-3-4-6-17(16)18/h3-8,11-13H,2,9-10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in hamster V79MZh cells using deoxycorticosterone as substrate				J Med Chem 57: 5179-89 (2014) Article DOI: 10.1021/jm500140c BindingDB Entry DOI: 10.7270/Q20Z74VS
					More data for this Ligand-Target Pair