Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cytochrome P450 26A1' and Ligand = 'BDBM476180'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 26A1 (Homo sapiens (Human))	BDBM476180 (US10874634, Cmpd No. 02 | US11364220, Compound 02) Show SMILES Cc1cc2c(cc1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H29NO3/c1-15-12-19-20(24(4,5)11-10-23(19,2)3)14-18(15)22(28)25-17-8-6-16(7-9-17)13-21(26)27/h6-9,12,14H,10-11,13H2,1-5H3,(H,25,28)(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B03
					More data for this Ligand-Target Pair
Cytochrome P450 26A1 (Homo sapiens (Human))	BDBM476180 (US10874634, Cmpd No. 02 | US11364220, Compound 02) Show SMILES Cc1cc2c(cc1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H29NO3/c1-15-12-19-20(24(4,5)11-10-23(19,2)3)14-18(15)22(28)25-17-8-6-16(7-9-17)13-21(26)27/h6-9,12,14H,10-11,13H2,1-5H3,(H,25,28)(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Queen''s University at Kingston US Patent					Assay Description CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...				US Patent US10874634 (2020) BindingDB Entry DOI: 10.7270/Q2Q52SP3
					More data for this Ligand-Target Pair